Silicon and bone health.
نویسنده
چکیده
Low bone mass (osteoporosis) is a silent epidemic of the 21st century, which presently in the UK results in over 200,000 fractures annually at a cost of over one billion pounds. Figures are set to increase worldwide. Understanding the factors which affect bone metabolism is thus of primary importance in order to establish preventative measures or treatments for this condition. Nutrition is an important determinant of bone health, but the effects of the individual nutrients and minerals, other than calcium, is little understood. Accumulating evidence over the last 30 years strongly suggest that dietary silicon is beneficial to bone and connective tissue health and we recently reported strong positive associations between dietary Si intake and bone mineral density in US and UK cohorts. The exact biological role(s) of silicon in bone health is still not clear, although a number of possible mechanisms have been suggested, including the synthesis of collagen and/or its stabilization, and matrix mineralization. This review gives an overview of this naturally occurring dietary element, its metabolism and the evidence of its potential role in bone health.
منابع مشابه
High Biological performance of Silicon Substituted Nano Hydroxyapatite Synthesized in Simulated Body Fluid at 37°C
In this work, we report high biological performance of silicon substituted nano hydroxyapatite (nHA) prepared by immersion of calcium phosphate and sodium silicate as precursors in Simulated Body Fluid (SBF) solution for 24, 36, 48 and 72 hrs at 37°C. Characterization and chemical analysis of the synthesized powders were performed by Fourier transform, infrared spectroscopy (FT-IR), X-ray powde...
متن کاملDietary silicon intake is positively associated with bone mineral density in men and premenopausal women of the Framingham Offspring cohort.
UNLABELLED The role of dietary silicon in bone health in humans is not known. In a cross-sectional, population-based study (2847 participants), associations between dietary silicon intake and BMD were investigated. Dietary silicon correlated positively and significantly with BMD at all hip sites in men and premenopausal women, but not in postmenopausal women, suggesting that increased silicon i...
متن کاملSilicon: A Review of Its Potential Role in the Prevention and Treatment of Postmenopausal Osteoporosis
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متن کاملHigh Biological performance of Silicon Substituted Nano Hydroxyapatite Synthesized in Simulated Body Fluid at 37°C
In this work, we report high biological performance of silicon substituted nano hydroxyapatite (nHA) prepared by immersion of calcium phosphate and sodium silicate as precursors in Simulated Body Fluid (SBF) solution for 24, 36, 48 and 72 hrs at 37°C. Characterization and chemical analysis of the synthesized powders were performed by Fourier transform, infrared spectroscopy (FT-IR), X-ray powde...
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عنوان ژورنال:
- The journal of nutrition, health & aging
دوره 11 2 شماره
صفحات -
تاریخ انتشار 2007